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Oral bacteria linked to Parkinson's via the gut-brain axis https://medicalxpress.com/news/2025-09-oral-bacteria-linked-parkinson-gut.html

Using mouse models, the researchers introduced S. mutans into the gut or engineered E. coli to express UrdA.

As a result, the mice showed elevated ImP levels in blood and brain tissue, along with the hallmark features of Parkinson's symptoms: loss of dopaminergic neurons, heightened neuroinflammation, impaired motor function, and increased aggregation of alpha-synuclein, a protein central to disease progression.