Federation isn’t just a feature, it’s how we reject oppression by design.
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Federation isn’t just a feature, it’s how we reject oppression by design.
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undefined notizie@poliverso.org shared this topic
Gli ultimi otto messaggi ricevuti dalla Federazione
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@ferrante @giornalismo un segnale forte che smentisce sondaggi fasulli a favore del governo del carovita
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MS also has lower resolution options. That can give you a rough idea of the weight, maybe of the parent molecule, and maybe some pieces and parts as it breaks into chunks. You might combine it with a front-end separation (like GC or HPLC) so you can analyze mixtures of molecules by separating them first then sending little tiny subsamples of them into the MS chamber as they come off a column.
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Sciopero generale della Cgil contro la manovra, mezzo milione in piazza
@giornalismo
articolo21.org/2025/12/scioper…
Mezzo milione di lavoratrici e lavoratori, pensionate e pensionati, cittadine e cittadini, hanno partecipato alle oltre cinquanta manifestazioni organizzate sul
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For MS, a HRMS (high resolution mass spectrometry) experiment is my first choice. That gives you the molecular ion to lots of decimal places and thus gives you the exact mass and thus empirical formula so you know what atoms and how many of them you are dealing with. It doesn’t give you structure, but it nails the empirical formula.
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(and in a funny twist, protein structure is usually figured out by X-ray crystallography. But proteins don’t normally exist in crystal form, they are fluidy-loosey-goosey flexible. Crystallization can introduce new conformational artifacts.
To get it right and determine the protein bonding interactions in native solution you use…..NMR!)
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The absolute best structural confirmation is single-crystal high resolution X-ray analysis. That gets you the positions and orientations of all the molecules. If it is a really highly resolved structure, you can see (or infer) the hydrogen atoms.
But X-ray crystallography is really hard (and expensive) to do right off the bat. NMR will always be the tool of choice.
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@mikkaels @ginopap @informapirata @informatica prendono in considerazione anche mastodon o il solo fatto di avere un social non allineato è motivo di esclusione?
