The Rubble of Memory
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The Rubble of Memory
A fleeting glimpse of a car on the highway sparks a journey back in time, a reflection on youth, lost dreams, and the powerful, deceptive nature of memory.
https://my-notes.dragas.net/2025/10/27/the-rubble-of-memory/
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Gli ultimi otto messaggi ricevuti dalla Federazione
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@ferrante @giornalismo un segnale forte che smentisce sondaggi fasulli a favore del governo del carovita
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MS also has lower resolution options. That can give you a rough idea of the weight, maybe of the parent molecule, and maybe some pieces and parts as it breaks into chunks. You might combine it with a front-end separation (like GC or HPLC) so you can analyze mixtures of molecules by separating them first then sending little tiny subsamples of them into the MS chamber as they come off a column.
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Sciopero generale della Cgil contro la manovra, mezzo milione in piazza
@giornalismo
articolo21.org/2025/12/scioper…
Mezzo milione di lavoratrici e lavoratori, pensionate e pensionati, cittadine e cittadini, hanno partecipato alle oltre cinquanta manifestazioni organizzate sul
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For MS, a HRMS (high resolution mass spectrometry) experiment is my first choice. That gives you the molecular ion to lots of decimal places and thus gives you the exact mass and thus empirical formula so you know what atoms and how many of them you are dealing with. It doesn’t give you structure, but it nails the empirical formula.
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(and in a funny twist, protein structure is usually figured out by X-ray crystallography. But proteins don’t normally exist in crystal form, they are fluidy-loosey-goosey flexible. Crystallization can introduce new conformational artifacts.
To get it right and determine the protein bonding interactions in native solution you use…..NMR!)
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#chatmail relays are recently getting more artful in their web presence 🤩 Nice examples:
https://darkrun.dev in Ontario, or
https://bloc7.icu/ in Warszaw.We estimate there are ~4 times more relays than in the published list at https://chatmail.at/relays
Many relays are smaller ones, but that's fine. A 5 EUR per month VPS can go a long way (thousands or tens of thousands of monthly users). Thanks for the service to all the operators of which around 40 are in a loose group chat 💗
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The absolute best structural confirmation is single-crystal high resolution X-ray analysis. That gets you the positions and orientations of all the molecules. If it is a really highly resolved structure, you can see (or infer) the hydrogen atoms.
But X-ray crystallography is really hard (and expensive) to do right off the bat. NMR will always be the tool of choice.
